An update on the management of cutaneous melanoma

An update in the management of malignant melanoma

Malignant melanoma is one of the most dangerous forms of cutaneous malignancies [1] . It is classified as cutaneous melanoma and non-cutaneous melanoma based on the location of the lesion. Ultraviolet (UV) radiation exposure is a predisposing factor for cutaneous melanoma, although in other forms such as mucous and anorectal malignant melanomas, ultraviolet radiation does not play a significant...

An Update On Natural Compounds and Their Modern Formulations for the Management of Malignant Melanoma

Primary Anorectal Melanoma: An Update

The anorectum is a rare anatomic location for primary melanoma. Mucosal melanoma is a distinct biological and clinical entity from the more common cutaneous melanoma. It portrays worse prognosis than cutaneous melanoma, with distant metastases being the overwhelming cause of morbidity and mortality. Surgery is the treatment of choice, but significant controversy exists over the extent of surgic...

P53 antigen expression in cutaneous Melanoma and its relation to tumor thickness

Background: P53 tumor suppressor gene mutation is one of the most common genetic alterations in human malignancies. The mutated from of the gene is stable and can be detected with immunohistochemistry methods. There is much controversy about the expression rate of this gene in malignant melanoma. Objective: To determine the frequency of the P53 antigen expression by sex, age, type and thickness...

Update on Clinical Trials for Malignant Melanoma